Whey and whey isolate comparison
Optimum Nutrition Platinum Hydrowhey vs Dymatize ISO100 Hydrolyzed
Dymatize ISO100 scores higher on our standard, 63/100 to 53/100. It earns more points for label transparency (fully disclosed vs added amino acids).
Both are scored out of 100 against our published standard: protein density, third-party testing, label transparency, sugar, ingredient simplicity and verified label data. Every number below is from the manufacturer's label; last checked 2026-10-13.
Optimum Nutrition
Platinum Hydrowhey
Side by side
Per serving, from each label. Bold marks the better score, protein density, sugar and cost where the two differ. How we score
| Compared | ON Platinum Hydrowhey | Dymatize ISO100 |
|---|---|---|
| Our score | 53/100 | 63/100 (better) |
| Protein density | 22 / 3073% of each scoop is protein | 22 / 3078% of each scoop is protein |
| Third-party testing | 0 / 25No verified independent testing program | 0 / 25No verified independent testing program |
| Label transparency | 10 / 20label lists added free amino acids, which can inflate a nitrogen-based protein number | 20 / 20 (better)Fully disclosed formula, no amino spiking |
| Sugar | 10 / 101 g sugar per serving | 10 / 101 g sugar per serving |
| Ingredient simplicity | 6 / 10Mix of natural and artificial flavors or sweeteners | 6 / 10Mix of natural and artificial flavors or sweeteners |
| Verified label data | 5 / 57 of 7 label values verified | 5 / 57 of 7 label values verified |
| Type | Hydrolyzed Whey | Whey Isolate |
| Protein per serving | 30 g | 25 g |
| Serving size | 41g (About 1 Scoop) | 1 scoop (32g) |
| Protein by weight | 73% | 78% (better) |
| Sugar | 1 g | 1 g |
| Calories | 140 | 120 |
| Cost per 25 g protein | Not verified | Not verified |
| Price per serving | Not verified | Not verified |
| Third-party certifications | None found | None found |
| Sweeteners | Sucralose, Acesulfame Potassium | Sucralose, Steviol Glycosides |
| Allergens | Milk, Soy | Milk, Soy |
| Proprietary blend | No | No |
| Added free amino acids (amino spiking) | Yes | No |
| Last checked | 2026-10-13 | 2026-10-13 |
Which to choose
Only the differences in our records. A value we couldn't verify never counts as a difference.
Choose ON Platinum Hydrowhey if…
- You want more protein per serving (30 g vs 25 g).
- You want a powder the brand labels gluten-free (our record for Dymatize ISO100 has no such label).
Choose Dymatize ISO100 if…
- You want more of each scoop to be protein (78% vs 73% by weight).
- You want fewer calories per serving (120 vs 140).
- You want a fully disclosed formula (ON Platinum Hydrowhey adds free amino acids).
- You want more flavors to choose from (16 vs 3).
The two powders
Good to know
Labels and prices change, so check the package before buying, especially if you have allergies. If you are pregnant, nursing, buying for a child or managing a health condition, ask your doctor before adding a supplement.