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Best Protein Powder

Whey and whey isolate comparison

Optimum Nutrition Gold Standard 100% Whey vs BSN Syntha-6

ON Gold Standard Whey scores higher on our standard, 78/100 to 41/100. It earns more points for protein density (77% vs 47% protein by weight), third-party testing (Informed Choice vs none found), sugar (1 g vs 3 g) and ingredient simplicity (mixed natural and artificial vs artificial flavors or sweeteners). Per 25 g of protein, ON Gold Standard Whey costs $1.86 and BSN Syntha-6 $1.80.

Both are scored out of 100 against our published standard: protein density, third-party testing, label transparency, sugar, ingredient simplicity and verified label data. Every number below is from the manufacturer's label; last checked 2026-10-14.

Optimum Nutrition

Gold Standard 100% Whey

Our score
78/100
Protein
24g
Per 25 g
$1.86
of protein
Informed Choice

BSN

Syntha-6

Our score
41/100
Protein
22g
Per 25 g
$1.80
of protein
No third-party testing found

Side by side

Per serving, from each label. Bold marks the better score, protein density, sugar and cost where the two differ. How we score

ON Gold Standard Whey and BSN Syntha-6 compared
ComparedON Gold Standard WheyBSN Syntha-6
Our score78/100 (better)41/100
Protein density22 / 30 (better)77% of each scoop is protein6 / 3047% of each scoop is protein
Third-party testing15 / 25 (better)Independently tested for contaminants or label accuracy0 / 25No verified independent testing program
Label transparency20 / 20Fully disclosed formula, no amino spiking20 / 20Fully disclosed formula, no amino spiking
Sugar10 / 10 (better)1 g sugar per serving6 / 103 g sugar per serving
Ingredient simplicity6 / 10 (better)Mix of natural and artificial flavors or sweeteners4 / 10Artificial flavors or sweeteners
Verified label data5 / 57 of 7 label values verified5 / 57 of 7 label values verified
TypeWhey BlendWhey Blend
Protein per serving24 g22 g
Serving size31g (About 1 Scoop)About 1 scoop (47 g)
Protein by weight77% (better)47%
Sugar1 g (better)3 g
Calories120190
Cost per 25 g protein$1.86$1.80 (better)
Price per serving$1.78$1.58
Third-party certificationsInformed ChoiceNone found
SweetenersAcesulfame PotassiumAcesulfame Potassium, Sucralose
AllergensMilk, SoyMilk, Soy
Proprietary blendNoNo
Added free amino acids (amino spiking)NoNo
Last checked2026-10-132026-10-14

Which to choose

Only the differences in our records. A value we couldn't verify never counts as a difference.

Choose ON Gold Standard Whey if…

  • You want independent testing for contaminants or label accuracy (Informed Choice); we found no third-party testing for BSN Syntha-6.
  • You want more protein per serving (24 g vs 22 g).
  • You want more of each scoop to be protein (77% vs 47% by weight).
  • You want less sugar (1 g vs 3 g per serving).
  • You want fewer calories per serving (120 vs 190).
  • You want a powder the brand labels gluten-free (our record for BSN Syntha-6 has no such label).
  • You want more flavors to choose from (22 vs 8).

Choose BSN Syntha-6 if…

On the label facts we track, BSN Syntha-6 has no clear edge over ON Gold Standard Whey. Taste, how it mixes and the price where you shop may still decide it.

The two powders

Optimum Nutrition

Gold Standard 100% Whey

Whey Blend · 31 g scoop
Informed Choice
Protein
24g
Sugar
1g
Our score
78/100
$1.78 / servingChecked 2026-10-13
BSN

Syntha-6

Whey Blend · 47 g scoop
No third-party testing found
Protein
22g
Sugar
3g
Our score
41/100
$1.58 / servingChecked 2026-10-14

Good to know

Labels and prices change, so check the package before buying, especially if you have allergies. If you are pregnant, nursing, buying for a child or managing a health condition, ask your doctor before adding a supplement.