Whey and whey isolate comparison
Optimum Nutrition Gold Standard 100% Whey vs Dymatize ISO100 Hydrolyzed
ON Gold Standard Whey scores higher on our standard, 78/100 to 63/100. It earns more points for third-party testing (Informed Choice vs none found). We could not verify a current price for Dymatize ISO100, so we can't compare cost.
Both are scored out of 100 against our published standard: protein density, third-party testing, label transparency, sugar, ingredient simplicity and verified label data. Every number below is from the manufacturer's label; last checked 2026-10-13.
Optimum Nutrition
Gold Standard 100% Whey
Side by side
Per serving, from each label. Bold marks the better score, protein density, sugar and cost where the two differ. How we score
| Compared | ON Gold Standard Whey | Dymatize ISO100 |
|---|---|---|
| Our score | 78/100 (better) | 63/100 |
| Protein density | 22 / 3077% of each scoop is protein | 22 / 3078% of each scoop is protein |
| Third-party testing | 15 / 25 (better)Independently tested for contaminants or label accuracy | 0 / 25No verified independent testing program |
| Label transparency | 20 / 20Fully disclosed formula, no amino spiking | 20 / 20Fully disclosed formula, no amino spiking |
| Sugar | 10 / 101 g sugar per serving | 10 / 101 g sugar per serving |
| Ingredient simplicity | 6 / 10Mix of natural and artificial flavors or sweeteners | 6 / 10Mix of natural and artificial flavors or sweeteners |
| Verified label data | 5 / 57 of 7 label values verified | 5 / 57 of 7 label values verified |
| Type | Whey Blend | Whey Isolate |
| Protein per serving | 24 g | 25 g |
| Serving size | 31g (About 1 Scoop) | 1 scoop (32g) |
| Protein by weight | 77% | 78% (better) |
| Sugar | 1 g | 1 g |
| Calories | 120 | 120 |
| Cost per 25 g protein | $1.86 | Not verified |
| Price per serving | $1.78 | Not verified |
| Third-party certifications | Informed Choice | None found |
| Sweeteners | Acesulfame Potassium | Sucralose, Steviol Glycosides |
| Allergens | Milk, Soy | Milk, Soy |
| Proprietary blend | No | No |
| Added free amino acids (amino spiking) | No | No |
| Last checked | 2026-10-13 | 2026-10-13 |
Which to choose
Only the differences in our records. A value we couldn't verify never counts as a difference.
Choose ON Gold Standard Whey if…
- You want independent testing for contaminants or label accuracy (Informed Choice); we found no third-party testing for Dymatize ISO100.
- You want a powder the brand labels gluten-free (our record for Dymatize ISO100 has no such label).
- You want more flavors to choose from (22 vs 16).
Choose Dymatize ISO100 if…
On the label facts we track, Dymatize ISO100 has no clear edge over ON Gold Standard Whey. Taste, how it mixes and the price where you shop may still decide it.
The two powders
Good to know
Labels and prices change, so check the package before buying, especially if you have allergies. If you are pregnant, nursing, buying for a child or managing a health condition, ask your doctor before adding a supplement.